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Hyponatraemia Guidelines If fluid status is unclear Therapeutic trial of 0.9% saline (e.g. 1 litre over 12 hours) and recheck Na+ after 6 hours. If hypovolaemic, Na+ should increase. Patients with SIADH … Hyponatraemia in adults (on or after 16th birthday). These guidelines have been published by the Guidelines & Audit Implementation Network (GAIN), which is a team of health care professionals … All qualified healthcare professionals who are involved in the investigation and treatment of adult inpatients with hyponatraemia. This guideline is to be used by qualified healthcare professionals to … All GAIN guidelines are currently reviewed on a three yearly basis. However, exceptions will be when there are changes in evidence on the existing benefits and harms of interventions or changes in … Moderate hyponatraemia (Na 115-125mmol/L) will need careful assessment. If there are any symptoms or there is a risk of the Na falling quickly admission may be appropriate. If a person has moderate or severe hyponatraemia and/or any symptoms, see the section on Admission or referral for more information on management. If a person has asymptomatic, mild hyponatraemia, … Therapy is guided by the rate of development and degree of hyponatraemia, accompanying symptoms, and the state of water balance, and should also consider the underlying cause. Severe hyponatraemia can be life threatening, requiring emergency assessment and treatment. This guidance covers emergency management of patients presenting with hyponatraemia associated with … Spasovski G et al. Clinical practice guideline on diagnosis and treatment of hyponatraemia. European Journal of Endocrinology (2014) 170, G1–G47. If a person presents with suspected malignant disease and hyponatraemia, SIADH should be suspected, and referral to the appropriate specialist via an urgent referral pathway is advised. With unexplained …